A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 31/4704 (2006.01) A61K 31/485 (2006.01) A61K 45/06 (2006.01) A61K 47/10 (2006.01)
Patent
CA 2477881
The present invention relates to a pharmaceutical formulation for use in the administration of a long-acting .szlig.2-agonist by inhalation. In particular this invention relates to a chemically stable highly efficient formoterol HFA solution formulation to be administered by pressurised metered dose inhalers (pMDIs) characterized by a deep lung penetration. The invention also relates to methods for the preparation of said formulation and to its use in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
La présente invention concerne une préparation pharmaceutique destinée à l'administration d'un agoniste .beta.2 à action prolongée par inhalation. Plus particulièrement, cette invention concerne une préparation de solution HFA de formotérol hautement efficace et chimiquement stable destinée à être administrée au moyen d'aérosols-doseurs pressurisés (PMDI) caractérisés par une pénétration pulmonaire profonde. L'invention se rapporte en outre à des procédés de fabrication de cette préparation, ainsi qu'à son utilisation pour traiter des maladies respiratoires telles que l'asthme et la bronchopneumopathie chronique obstructive (BPCO).
Brambilla Gaetano
Church Tanya Kathleen
Davies Rebecca Jaine
Ferraris Alessandra
Ganderton David
Chiesi Farmaceutici S.p.a.
Kirby Eades Gale Baker
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