Forms of factor xiia

C - Chemistry – Metallurgy – 12 – N

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C12N 9/64 (2006.01) C07K 16/40 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2609109

A 53Kd novel form of factor XIIa and related products, including nucleic acid molecules, monoclonal and polyclonal antibodies and hybridoma cell lines. Also assays for a 53Kd form of factor XIIa and uses of said assays in diagnostic and prognostic methods, for example in the prediction of survival following myocardial infarction.

La présente invention concerne une nouvelle forme 53Kd du facteur XIIa et des produits associés, y compris des molécules d'acide nucléique, de anticorps monoclonaux et polyclonaux et des lignées cellulaires d'hybridome. L'invention concerne également des dosages biologiques pour une forme 53Kd du facteur XIIa et les utilisations de ces dosages biologiques dans des procédés de diagnostic et de pronostic, par exemple, pour prédire la survie après un infarctus du myocarde.

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