Formulation and use of carotenoids in treatment of cancer

Details Formulation and use of carotenoids in treatment of cancer Formulation and use of carotenoids in treatment of cancer

A - Human Necessities

61

K

A61K 31/20 (2006.01) A61K 9/127 (2006.01) A61K 31/203 (2006.01)

Patent

CA 2128103

A reduced-toxicity formulation of carotenoids is disclosed which is stable in an aqueous environment. The formulation includes a carotenoid, lipid carrier particles (such as liposomes), and an intercalation promoter agent (such as a triglyceride), which causes the carotenoid to be substantially uniformly distributed with the lipid in the lipid carrier particles. The molar ratio of carotenoid to lipid is greater than about 1:10. Also disclosed is a method of inhibiting the growth of cancer cells, which comprises administering to a living subject a therapeutically effective amount of a composition as described above.

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