Formulation comprising antibacterial substance and antiulcer...

Details Formulation comprising antibacterial substance and antiulcer... Formulation comprising antibacterial substance and antiulcer...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/43 (2006.01) A61K 31/44 (2006.01) A61K 31/65 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2131569

Abstract of the Disclosure The present invention includes a formulation which comprises an antibacterial substance and an antiulcer substance, wherein at least one of them is formulated into a gastrointestinal mucosa-adherent solid preparation. The formulation of the present invention shows long retention time in the gastrointestinal tract because of adhesion to the gastrointestinal tract mucosa, synergetically enhances the pharmaceutical effects of the antibacterial substance, specially antibiotic against Helicobacter pylori (HP) and the antiulcer substance, with very low doses of active ingredients, particularly the anti-HP antibiotic with low prevalence of side effects. The present agent is useful as an antiulcer agent, showing potent anti-HP activity.

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