A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/352 (2006.01) A61K 36/18 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2537459
The present invention provides a novel method for preventing and treating memory and cognitive impairment resulting from oxidative stress, inflammation and the process of aging, as well as, neurodegenerative conditions. The method is comprised of administering a composition comprising a mixture of Free-B- Ring flavonoids and flavans synthesized and/or isolated from a single plant or multiple plants to a host in need thereof. The present also includes a novel method for simultaneously inhibiting expression of pro-inflammatory cytokines, preventing ROS generation and augmenting anti-oxidant defenses. The activity of this composition is conducive to ultimately preserving cognitive function and providing a level of neuroprotection.
L'invention concerne un nouveau procédé pour prévenir et traiter des anomalies cognitives et les troubles de la mémoire provoqués par le stress oxydatif, l'inflammation et la vieillesse, ainsi que des états pathologiques neurodégénératifs. Ledit procédé comprend l'administration d'une composition comprenant un mélange de flavonoïdes et flavanes à cycle B synthétisés et/ou isolés à partir d'une ou de plusieurs plantes chez un hôte nécessitant le traitement. L'invention concerne également un nouveau procédé pour inhiber simultanément l'expression des cytokines pro-inflammatoires, pour prévenir la production de ROS et pour augmenter les défenses antioxydantes. L'activité de ladite composition vise à préserver la fonction cognitive et à fournir un niveau de neuroprotection.
Burnett Bruce
Jia Qi
Zhao Yuan
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Unigen Inc.
Unigen Pharmaceuticals Inc.
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