Formulation of nucleic acids and acemannan

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2308444

The present invention is related to the medical field, and in particular to the use of new formulations of adjuvants with vaccine antigens. The technical object of the invention is the development of formulations which are capable of potentiating the immune response of the organism to vaccines of nucleic acids. In order to attain this objective, a formulation has been developed which contains as fundamental components the vaccine nucleic acid and acemannan in adequate proportions, in addition to stabilizing and preservative agents. The formulations of the invention are applicable to the pharmaceutical industry as vaccine formulations both for human and animal use.

L'invention concerne le domaine de la médecine et en particulier l'utilisation de nouvelles formulations d'adjuvants avec des antigènes vaccinaux. L'objectif technique de l'invention est le développement de formulations capables de potentialiser la réponse immune de l'organisme à des vaccins d'acides nucléiques. Afin d'atteindre cet objectif, on a développé une formulation qui contient en tant que composants fondamentaux l'acide nucléique vaccinal et l'acémannane dans des proportions adéquates, ainsi que des agents de stabilisation et de conservation. Les formulations de cette invention s'appliquent dans l'industrie pharmaceutique en tant que formulations vaccinales à la fois pour l'homme et l'animal.

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