A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/22 (2006.01) A61K 9/08 (2006.01) A61K 39/395 (2006.01) A61K 47/18 (2006.01)
Patent
CA 2672902
The invention provides a formulation comprising a buffer with a pH from about 4.0 to about 6.0, proline and an effective amount of a polypeptide. The polypeptide can be an antibody. The specification also provides methods of preparing the formulation, a kit containing the formulation and methods of using the formulation.
L'invention concerne une formulation comprenant un tampon présentant un pH compris entre 4,0 environ et 6,0 environ, de la proline et une quantité efficace d'un polypeptide. Ce polypeptide peut être un anticorps. L'invention concerne également des procédés de préparation de cette formulation, un kit contenant cette formulation et des procédés d'utilisation de cette formulation.
Brems David
Gokarn Yatin R.
Jacob Jaby
Matsumura Masazumi
Amgen Inc.
Gowling Lafleur Henderson Llp
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