Formulations and methods for providing prolonged local...

Details Formulations and methods for providing prolonged local... Formulations and methods for providing prolonged local...

A - Human Necessities

61

K

A61K 31/4458 (2006.01) A61K 31/167 (2006.01) A61K 31/245 (2006.01) A61K 31/56 (2006.01) A61K 45/08 (2006.01) A61P 23/02 (2006.01)

Patent

CA 2349017

A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when implanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.

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