Formulations and methods of administration of...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/147 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 419/14 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2492456

The present invention is directed to compositions and methods for the treatment of patients with cephalotaxines, for example, homoharringtonine. The invention is also directed to improvements in the purity, manufacturing process, formulation and administration of homoharringtonine for the treatment of cancer and other aberrant cellular diseases. The invention also provides methods and compositions for antiparasitic, antifungal, antiviral and antibacterial treatments.

la présente invention concerne des compositions et des méthodes de traitement de patients à l'aide de céphalotaxines, tels que l'homoharringtonine. L'invention porte également sur des améliorations apportées en termes de pureté, de procédé de fabrication, de formulation et d'administration d'homoharringtonine pour le traitement du cancer et autres maladies liées à une aberration de la prolifération cellulaire. Par ailleurs, l'invention concerne des méthodes et des compostions thérapeutiques antiparasitaires, antifongiques, antivirales et antibactériennes.

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