Formulations and polymorphic forms of desferrioxamine and...

Details Formulations and polymorphic forms of desferrioxamine and... Formulations and polymorphic forms of desferrioxamine and...

C - Chemistry, Metallurgy

07

C

C07C 259/06 (2006.01) A61K 31/16 (2006.01)

Patent

CA 2274761

A parenterally injectable composition comprising particles of a desferrioxamine-B salt of an aliphatic sulphonic acid having at least 8 carbon atoms suspended in a parenterally administrable oil. New crystalline modifications of desferrioxamine B decanesulphonic salt are provided, and one crystal form with outstanding stability is disclosed.

L'invention concerne une composition pouvant être injectée par voie parentérale. Cette composition comprend des particules d'un sel desferrioxamine-B d'un acide sulfonique aliphatique comprenant au moins 8 atomes de carbone en suspension dans une huile pouvant être administrée par voie parentérale. L'invention concerne également de nouvelles modifications cristallines de sel décanésulfonique de desferrioxamine B, et une forme cristalline avec une meilleure stabilité.

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