Formulations and their use in the treatment of neurological...

Details Formulations and their use in the treatment of neurological... Formulations and their use in the treatment of neurological...

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 9/50 (2006.01) A61K 9/70 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2054822

Pharmaceutical formulations comprise a mono- or di-aminopyridine active agent for administration on a once- or twice-daily basis for use in the treatment of neurological diseases, in particular multiple sclerosis and Alzheimer's disease. The formulations, which are suitable for oral or percutaneous administration of the active agent, include the active agent in a carrier effective to permit release of the mono- or di-aminopyridine at a rate allowing controlled absorption thereof over, on the average, not less than a 12 hour period and at a rate sufficient to achieve therapeutically effective blood levels over a period of 12-24 hours following administration.

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