C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/06 (2006.01) A61K 31/661 (2006.01)
Patent
CA 2584537
The invention relates to novel medicament formulations containing, as active ingredients, alkylphosphocholines and the like, alkyl-alkanediol- phosphocholines and the like, and (ether)lysolecithines and the like, in different forms of embodiment. Said active ingredients are integral constituents of liposomes, also containing cholesterol and the like and a negative charge carrier. The medicament formulations are especially suitable for the treatment and/or prophylaxis of cancer, protozoan diseases such as leishmaniasis and amoebic diseases, acariasis and diseases caused by arthropods, and bacterial diseases, such as ehrlichiosis. Ocular diseases accompanied by uncontrolled cellular processes can also be advantageously influenced.
La présente invention concerne de nouvelles formulations médicamenteuses contenant, en tant qu'agents actifs, alkylphosphocholines et analogues, alkyl-alcanediol-phosphocholines et analogues, et (éther)-lysolécithines et analogues dans divers modes de réalisation. Lesdits agents actifs sont des composants entiers de liposomes contenant également des cholestérols et analogues ainsi qu'un porteur de charge négatif. Lesdites formulations médicamenteuses sont particulièrement adaptées au traitement et/ou à la prophylaxie du cancer, de protozooses telles que les leishmanioses et les amibiases, d'acarioses et de maladies dues à des arthropodes, ainsi que de maladies bactériennes telles que par ex. l'ehrlichiose. Des maladies oculaires accompagnées de processus cellulaires incontrôlés peuvent être influencées de façon avantageuse.
Eibl Hansjorg
Steffan Jean
Wieland-Berghausen Susanne Christine
Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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