Formulations containing amide derivatives of carboxylic acid...

A - Human Necessities – 61 – K

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A61K 31/165 (2006.01) A61K 9/00 (2006.01) A61K 31/166 (2006.01) A61K 31/403 (2006.01) A61K 47/02 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2649471

Topical compositions of amide derivatives of carboxylic acid non-steroidal anti-inflammatory agents are disclosed. The compositions have a reduced potential to cause mitochondrial swelling when topically administered to the eye.

La présente invention concerne des compositions pour administration locale de dérivés amides d'agents anti-inflammatoires non stéroïdiens de type acide carboxylique. Les compositions présentent une capacité réduite à provoquer le gonflement des mitochondries lorsqu'elles sont administrées localement au niveau de l'AEil.

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