Formulations containing esculoside and the use thereof in...

A - Human Necessities – 61 – K

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A61K 31/7048 (2006.01) A61K 8/49 (2006.01) A61K 8/60 (2006.01) A61K 8/97 (2006.01) A61K 31/352 (2006.01) A61K 31/522 (2006.01) A61K 31/70 (2006.01) A61Q 19/06 (2006.01)

Patent

CA 2153604

The present invention relates to the use of esculoside alone or in combination with adenylate cyclase stimulators, such as forskolin or Salvia miltiorrhiza diterpenes and/or with phosphodiesterase inhibitors, such as apigenine-skeleton dimeric flavones, in topical formulations for the treatment of peripheral vasculopathies related to an impaired peripheral microcirculation, cellulitis or unesthetisms connected with a deposit of superfluous fat. For the reduction of the deposits of superfluous fat of any origin, the above mentioned products are advantageously also combined with caffeine, theophylline and derivatives thereof.

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