Formulations containing melatonin to be topically applied...

Details Formulations containing melatonin to be topically applied... Formulations containing melatonin to be topically applied...

A - Human Necessities

61

K

A61K 8/49 (2006.01) A61K 8/64 (2006.01) A61Q 17/00 (2006.01) A61Q 19/00 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2230389

A method is disclosed for the utilization of topically applied melatonin for the prevention of oxidative damage in human skin induced by sunlight; i.e., a method for preparing formulations containing melatonin for use as moisturizers, sunblocks, and sunscreens. In addition the formulations will contain one or more proteins that will preserve the melatonin from degradation while in storage, but will allow its controlled release for penetration into cells of the skin when topically applied to the skin, in such a manner that serum melatonin concentration is not raised to supra-physiological levels that may induce adverse effects. In addition the formulation may optionally contain other antioxidants and cosmetic agents.

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