Formulations for hydrophobic pharmaceutical agents

A - Human Necessities – 61 – K

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Details

A61K 31/404 (2006.01) A61K 31/427 (2006.01) A61K 31/517 (2006.01) A61K 47/10 (2006.01) A61K 47/30 (2006.01) A61K 47/44 (2006.01) A61P 35/00 (2006.01) G01N 33/15 (2006.01)

Patent

CA 2282439

The field of the invention is inducible gene expression systems wherein expression is controlled by a novel ecdysone receptor or its derivatives. The field particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel ecdysone receptor. The nucleic acid and polypeptides are useful in novel gene expression systems inducible with ecdysone or derivative receptor agonists.

L'invention porte sur des préparations contenant des préparations pharmaceutiques liquides, semi-solides ou solides améliorant la biodisponibilité orale d'agents pharmaceutiques hydrophobes, tels que des composés à base de quinazoline, de nitrothiazole, et d'indolinone. L'invention porte également sur des préparations servant à l'administration parentérale de tels agents pharmaceutiques hydrophobes, ainsi que sur des procédés d'obtention et d'utilisation des deux types de préparations.

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