A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/565 (2006.01) A61K 9/08 (2006.01) A61K 31/335 (2006.01) A61K 31/40 (2006.01) A61K 31/47 (2006.01) A61K 31/475 (2006.01) A61K 31/555 (2006.01) A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 33/00 (2006.01) A61K 38/38 (2006.01) A61K 47/42 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2380312
A pharmaceutical formulation which comprises a parenterally acceptable carrier or a diluent and estramustine phosphate in admixture with human albumin, wherein the weight ratio of estramustine phosphate to human albumin is from about 1:5 to about 1:0.3. The formulation can be administered according to a combined chemotherapy regimen in association with one or more chemotherapeutic agents. The formulation also enables estramustine phosphate to be administered with no side effects at the side of injection.
La présente invention concerne une formulation pharmaceutique comprenant un support ou un véhiculant, acceptable par voie parentérale, et du phosphate d'estramustine, en adjonction avec de l'albumine humaine. Le rapport en poids du phosphate d'estramustine sur l'albumine humaine est d'environ 1:5 à environ 1:0,3. Ladite formulation peut être administrée selon un schéma posologique de chimiothérapie combinée, en association avec un ou plusieurs agents chimiothérapeutiques. La formulation selon l'invention permet également une administration de phosphate d'estramustine sans effets secondaires sur le site d'injection.
Buzzi Giovanni
Colombo Paolo
Martini Alessandro
Muggetti Lorena
Pharmacia Italia Spa
Smart & Biggar
LandOfFree
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