Formulations for parenteral use of estramustine phosphate...

Details Formulations for parenteral use of estramustine phosphate... Formulations for parenteral use of estramustine phosphate...

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/08 (2006.01) A61K 31/198 (2006.01) A61K 31/66 (2006.01) A61K 31/661 (2006.01) A61K 45/06 (2006.01) A61K 47/18 (2006.01) A61P 35/00 (2006.01) A61K 47/40 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2384726

A pharmaceutical formulations which comprises a parenterally acceptable carrier or diluent and estramustine phosphate and a basic amino acid. The formulation can be administered according to a combined chemotherapy regimen in association with one or more chemotherapeutic agents. The formulation also enables the estramustine phosphate to be administered with no side effects at the site of injection.

L'invention concerne une formulation pharmaceutique comprenant un excipient ou un diluant acceptable d'un point de vue parentéral, un phosphate d'estramustine et un acide aminé de base. La formulation peut être administrée selon un régime de chimiothérapie combinée associé à un ou plusieurs agents chimiothérapeutiques. Cette formulation permet également d'administrer le phosphate d'estramustine sans effets secondaires sur le site d'injection.

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