Formulations for parenteral use of estramustine phosphate...

Details Formulations for parenteral use of estramustine phosphate... Formulations for parenteral use of estramustine phosphate...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 31/565 (2006.01) A61K 31/66 (2006.01) A61K 38/38 (2006.01) A61K 47/40 (2006.01) A61K 47/42 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2385063

A pharmaceutical formulation which comprises a parenterally acceptable carrier or diluent, estramustine phosphate, a sulfoalkyl ether cyclodextrin and human albumin. The formulation can be administered according to a combined chemotherapy regimen in association with one or more chemotherapeutic agents. The formulation also enables the estramustine phosphate to be administered with no side effects at the site of injection.

L'invention concerne une formulation pharmaceutique renfermant un excipient ou diluant acceptable par voie parentérale, de l'estramustine phosphate, une cyclodextrine de sulfoalkyl éther et de l'albumine humaine. La formulation peut être administrée selon un schéma posologique chimiothérapeutique combiné, en association avec un ou plusieurs agents chimiomothérapeutiques. La formulation permet aussi d'administrer l'estramustine phosphate sans effets secondaires au site d'injection.

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