Formulations for recombinant beta-interferon

Details Formulations for recombinant beta-interferon Formulations for recombinant beta-interferon

C - Chemistry, Metallurgy

12

P

167/103, 195/74,

C12P 21/02 (2006.01) A61K 38/21 (2006.01) C07K 14/55 (2006.01) C07K 14/565 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339707

An improved process for recovering and purifying recombinant beta-interferon from its host yields a beta-interferon preparation which may be formulated into a stable pharmaceutical composition having a therapeutically effective amount of the biologically active recombinant beta-interferon dissolved in a non-toxic, inert, therapeutically compatible aqueous-based carrier medium at a pH of 2 to 4 which medium also contains a stabilizer for the recombinant beta-interferon, such as human serum albumin, normal serum albumin and human plasma protein fraction.

516417

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