Formulations for sustained release dressings and their use

Details Formulations for sustained release dressings and their use Formulations for sustained release dressings and their use

A - Human Necessities

61

K

167/159, 167/166

A61K 47/38 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/70 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2027864

The invention concerns a sustained release formulation comprising an agent (A) which is to be released and a vehicle (B) therefor. The vehicle comprises a hydrophilic component such as a polyhydroxylated organic substance such as a polyethylene glycol, glycerol, sorbitol, mannitol or lactose and curable silicone composition which is capable of curing at ambient temperature and contains a polysiloxane having alkyhydrogen units, a polysiloxane having unsaturated groups and a platinum or rhodium catalyst. The formulation may be applied to the human or animal body or a cavity in the latter to cure in situ to give a dressing capable of sustained release of the therapeutic or diagnostic agent (A) to the body. The invention is applicable in the field of pharmacy.

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