Formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives

Details Formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives Formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives

A - Human Necessities

61

K

A61K 31/5513 (2006.01) A61K 9/28 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2586124

The present invention provides solid dosage formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives and processes for their manufacture. In some particular embodiments, the present invention provides novel formulations of the antipsychotic and antiobesity agent (9aR, 12aS)- 4,5,6,7,9,9a,10,11,12,12a~decahydrocyclopenta[c][1,4]diazepino[6,7,1- ij]quinoline hydrochloride (Compound A-HCI).

L'invention concerne des formulations de dosage solides de dérivés de [1,4]diazépino[6,7,1-IJ]quinoline et des procédés de production associés. Dans certains modes de réalisation spécifiques, l'invention concerne des nouvelles formulations de l'agent antipsychotique et antiobésité hydrochlorure de (9aR, 12aS)-4,5,6,7,9,9a,10,11,12,12a-décahydrocyclopenta[c][1,4]diazépino[6,7,1-IJ]quinoline (composé A-HCI).

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