Formulations of low dose non-steroidal anti-inflammatory...

A - Human Necessities – 61 – K

Patent

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A61K 47/40 (2006.01) A61K 31/12 (2006.01) A61K 31/185 (2006.01) A61K 31/40 (2006.01) A61K 31/42 (2006.01) A61K 31/435 (2006.01) A61K 31/5415 (2006.01) A61K 31/635 (2006.01) A61K 45/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2647533

The present invention is directed to pharmaceutical compositions containing (a) a dosage of a non-steroidal anti-inflammatory drug (NSAID) effective to induce analgesia an anti-inflammatory effect, or an anti-pyretic effect and (b) a beta-cyclodextrin compound; wherein the dosage of the NSAID compound is less than the minimum approved dose for the route of administration. Additionally, the present invention is directed to methods for treating a mammal in need of an analgesic, an anti-inflammatory, or an anti-pyretic agent comprising administering the pharmaceutical composition of the present invention.

La présente invention concerne des compositions pharmaceutiques contenant (a) une dose de médicaments anti-inflammatoires non stéroïdiens (AINS), efficace pour induire un effet analgésique et anti-inflammatoire ou un effet anti-pyrétique et (b) un composé de bêta-cyclodextrine, le dosage du composé AINS étant inférieur à la dose minimale approuvée pour le mode d'administration. De plus, la présente invention concerne des procédés permettant de traiter un mammifère nécessitant un analgésique, un anti-inflammatoire, ou un agent anti-pyrétique, lesdits procédés consistant à administrer la composition pharmaceutique de la présente invention.

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