Formulations of ob protein

A - Human Necessities – 61 – K

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A61K 47/26 (2006.01) A61K 9/19 (2006.01) A61K 38/22 (2006.01)

Patent

CA 2250570

The present invention provides lyophilized compositions of an obesity protein. The compositions demonstrate remarkable stability and ease of manufacture and, significantly, are useful to prepare stable pharmaceutical formulations useful for treating patients in need thereof. Thus, the invention further provides methods of using such formulations for the treatment of obesity and disorders associated with obesity such as diabetes, cardiovascular disease and cancer.

L'invention se rapporte à des compositions lyophilisées d'une protéine de l'obésité. Ces compositions manifestent une stabilité remarquable, sont faciles à produire et, notablement, peuvent servir à la préparation de formulations pharmaceutiques stables, utiles au traitement de patients. L'invention fournit en outre des procédés d'utilisation de telles formulations, destinées au traitement de l'obésité et de troubles associés à l'obésité, tels que des diabètes, des maladies cardio-vasculaires et des cancers.

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