Fractal-forming alkylketene dimers for integral membrane...

B - Operations – Transporting – 01 – D

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B01D 9/00 (2006.01)

Patent

CA 2540331

This invention provides a device for promoting crystallization of integral membrane proteins using a surface of alkylketene dimers doped with a nucleating compound. A coating that enhances crystallization of integral membrane proteins in the presence of detergent is provided. In another aspect of the invention methods of creating a surface of alkylketene dimers doped with a nucleating compound to promote crystallization of integral membrane proteins are provided. In another aspect of the invention methods of crystallizing integral membrane proteins using surfaces coated with alkylketene dimers doped with a nucleating compound are provided.

L'invention concerne un dispositif permettant de favoriser la cristallisation de protéines membranaires intrinsèques au moyen d'une surface de dimères d'alkylcétène dopés par un composé de nucléation. Un revêtement qui améliore la cristallisation de protéines membranaires intrinsèques en présence d'un détergent est utilisé. L'invention concerne, selon un autre aspect, des procédés de création d'une surface de dimères d'alkylcétène dopés par un composé de nucléation afin de favoriser la cristallisation de protéines membranaires intrinsèques. L'invention concerne, selon un autre aspect, des procédés de cristallisation de protéines membranaires intrinsèques au moyen de surfaces revêtues par des dimères d'alkylcétène dopés par un composé de nucléation.

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