Fractional precipitation of gamma globulin with polyethylene...

Details Fractional precipitation of gamma globulin with polyethylene... Fractional precipitation of gamma globulin with polyethylene...

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) C07K 16/06 (2006.01)

Patent

CA 1064396

Abstract of the Disclosure A process is provided for the preparation of a gamma globulin suitable for intravenous administration from the readily available fraction II + III plasma protein paste. The fraction II ? III paste is extracted with water at a pH of 4.8 - 6.5 and impurities are fractionally precipitated by addition of polyethylene glycol to 4% of wt./vol. and then 5% wt./vol. The desired gamma globulin is then precipitated at a pH 8.0 by addition of polyethylene glycol to 12% wt./vol.

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