Fractionation of proteins by electrical means

A - Human Necessities – 61 – K

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167/114, 204/98.

A61K 35/16 (2006.01) A23J 1/06 (2006.01) B01D 57/02 (2006.01) G01N 33/487 (2006.01)

Patent

CA 1043703

ABSTRACT A process for the fractionation of liquid solutions of protein mixtures which includes the steps of subjecting such solutions to electrodialysis in the pH range 4.8 to 6, until desalting of the solution commences, said electrodialysis being conducted at temperature below 15°C: and continuing said electrodialysis until the specific resistance of the mixture exceeds 1000 ohm-cm whereby a fraction of said protein mixture precipitates; and recovering the dialysate. Another aspect of the invention is an albumin concentrate for use in the preparation of plasma extenders, having at least 90% albumin, free from salts, euglobulins and euglobulin- like materials.

225941

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