A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/29 (2006.01)
Patent
CA 2302255
The present invention provides methods of bone healing and fracture repair comprising administering to a patient in need thereof an effective amount of a polypeptide analog of parathyroid hormone related peptide (PTHrP) and salts thereof, wherein amino acid residues 22-31 form an amphipathic .alpha.-helix or the use of such a polypeptide for the preparation of a medicament for the treatment of bone healing and fracture repair.
L'invention concerne des procédés de guérison et de réparation de fractures, ce qui consiste à administrer au malade une quantité efficace d'un analogue polypeptidique d'un peptide apparenté à l'hormone de parathyroïde (PTHrP) et ses sels, dans lesquels les résidus aminoacides 22-31 constituent une .alpha.-hélice amphipathique, ou à utiliser ce polypeptide afin de préparer un médicament servant à la guérison et à la réparation de fractures.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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