Fragmentation resistant igg1 fc-conjugates

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/00 (2006.01)

Patent

CA 2758524

The present invention provides compositions and methods relating to human IgG1 and IgG3 Fc-conjugates which are resistant to free-radical mediated fragmentation and aggregation. The present invention also provides compositions and methods for making the Fc-conjugates of the invention.

La présente invention porte sur des compositions et procédés concernant des conjugués IgG1 et IgG3 humaines-Fc, qui sont résistants à une fragmentation et à une agrégation médiation par des radicaux libres. La présente invention porte aussi sur des compositions et procédés pour préparer les conjugués Fc de l'invention.

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