C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01)
Patent
CA 2758524
The present invention provides compositions and methods relating to human IgG1 and IgG3 Fc-conjugates which are resistant to free-radical mediated fragmentation and aggregation. The present invention also provides compositions and methods for making the Fc-conjugates of the invention.
La présente invention porte sur des compositions et procédés concernant des conjugués IgG1 et IgG3 humaines-Fc, qui sont résistants à une fragmentation et à une agrégation médiation par des radicaux libres. La présente invention porte aussi sur des compositions et procédés pour préparer les conjugués Fc de l'invention.
Hu Zhonghua
Kleemann Gerd Richard
Yan Boxu
Yates Zachary Adam
Zhou Hongxing
Amgen Inc.
Smart & Biggar
LandOfFree
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