Framework selection

Details Framework selection Framework selection

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01)

Patent

CA 2656047

The present invention relates to improved methods for the selection of appropriate human acceptor framework regions for non-human (donor) antibodies and methods for obtaining humanized antibodies of high affinity using such acceptor frameworks.

L'invention concerne des méthodes améliorées servant à sélectionner des zones d'infrastructure appropriées d'accepteurs humains pour des anticorps non humains (donneurs), ainsi que des méthodes servant à obtenir des anticorps humanisés d'affinité élevée au moyen de ces infrastructures d'accepteurs.

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