A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 15/32 (2006.01) A61L 15/28 (2006.01) A61F 13/00 (2006.01) A61L 2/08 (2006.01)
Patent
CA 2347331
The invention provides a sterile freeze-dried sponge, wherein at least 80% by weight of the sponge consists of collagen and oxidized regenerated cellulose in the weight ratio 60:40 to 40:60, wherein the sponge has a dry tensile strength of more than 3N and/or a wet tensile strength of more than 1 N. Preferably, the collagen has a degree of denaturation less than 20% and the sponge is substantially free of chemical cross-links. The invention also provides methods for the manufacture of sponges according to the invention
L'invention concerne une éponge lyophilisée stérile, dans laquelle au moins 80 % de l'éponge en poids est constitué de collagène et de cellulose régénérée oxydée dans un rapport en poids de 60/40 à 40/60, dans laquelle l'éponge a une résistance à la traction à sec de plus de 3N et/ou une résistance à la traction au mouillé de plus de 1 N. De préférence, le collagène a un degré de dénaturation de moins de 20 % et l'éponge est pratiquement exempte de liaisons transversales chimiques. L'invention présente également des méthodes pour la fabrication d'éponges.
Aitken Will
Harvey Wil
Hyland Tom
Van Leeuwen Peter
Johnson & Johnson Medical Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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