Freeze dried liposome encapsulated amphiphilic drug...

Details Freeze dried liposome encapsulated amphiphilic drug... Freeze dried liposome encapsulated amphiphilic drug...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 31/195 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2253974

A process for the preparation of freeze dried liposome encapsulated amphiphilic drug compositions, which process comprises preparing a liposomal suspension of multilamellar vesicles (MLVs) which encapsulate an amphiphilic drug composition, adding sorbitol to the liposomal suspension and lyophilisation of the suspension.

L'invention concerne un procédé de préparation de compositions médicamenteuses amphiphiles et lyophilisées, encapsulées dans des liposomes. Ledit procédé consiste à préparer une suspension liposomale de vésicules multilamellaires qui encapsulent une composition médicamenteuse amphiphile, à ajouter du sorbitol à la suspension liposomale et à lyophiliser la suspension.

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