Fructosamine oxidase: antagonists and inhibitors

Details Fructosamine oxidase: antagonists and inhibitors Fructosamine oxidase: antagonists and inhibitors

A - Human Necessities

61

K

A61K 31/15 (2006.01) A61K 31/132 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) A61K 31/175 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/4172 (2006.01) A61K 31/4375 (2006.01) A61K 31/44 (2006.01) A61K 31/498 (2006.01) A61K 31/50 (2006.01) A61K 31/655 (2006.01) A61K 45/00 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2344690

Methods of reducing the consequences of macrovascular and microvascular damage in a diabetic patient reliant upon the inhibition and/or antagonism of Fructosamine oxidase in the patient. Inhibition and/or antagonism can involve the use of copper chelating agents, substrate analogues or hydrazine compounds.

Cette invention se rapporte à des procédés servant à réduire les conséquences des dommages macrovasculaires et microvasculaires chez un patient diabétique, en recourant à l'inhibition et/ou l'antagonisme de la fructosamine-oxydase chez ce patient. Cette inhibition et/ou cet antagonisme peuvent impliquer l'utilisation d'agents de chélation au cuivre, d'analogues substrats ou de composés hydrazine.

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