Fructosamine oxidase assay: methods and materials

Details Fructosamine oxidase assay: methods and materials Fructosamine oxidase assay: methods and materials

C - Chemistry, Metallurgy

12

Q

C12Q 1/26 (2006.01) C12N 9/02 (2006.01) C12N 9/06 (2006.01) G01N 33/573 (2006.01) G01N 33/66 (2006.01)

Patent

CA 2343357

Methods whereby, by reference to fructosamine oxidase activity in blood plasma of a patient or patients, the risk of diabetes associated vascular complications can be assessed, candidate fructosamine oxidase inhibitors and/or antagonists can be identified or tested and the inhibition and/or antagonism of the fructosamine oxidase inhibition and/or antagonism of a patient can be assessed.

Cette invention se rapporte à des procédés grâce auxquels, par référence à l'activité de la fructosamine-oxydase dans le plasma sanguin d'un patient ou d'un groupe de patients, le risque de diabète associé à des complications vasculaires peut être évalué, les inhibiteurs et/ou les antagonistes candidats de la fructosamine-oxydase peuvent être identifiés et testés, et l'effet inhibiteur et/ou l'antagonisme de l'effet inhibiteur de la fructosamine-oxydase et/ou l'antagonisme d'un patient peuvent être évalués.

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