Fsh and fsh variant formulations, products and methods

Details Fsh and fsh variant formulations, products and methods Fsh and fsh variant formulations, products and methods

A - Human Necessities

61

K

A61K 38/24 (2006.01) A61P 15/08 (2006.01) C07K 14/59 (2006.01)

Patent

CA 2335340

This invention relates to FSH or a FSH variant containing an alpha and beta subunit contained in formulations, and articles of manufacture. The invention provides advantageous new proteins and nucleic acids, multi-use pharmaceutical solutions, formulations and products of said proteins and nucleic acids where none approved for commercial use had previously existed having such extended use indications. These products are particularly useful in therapeutic regimens for increasing serum levels of FSH or a FSH variant over a period of treatment. Thus, inter alia, the invention fills the need for convenient products of FSH or from a FSH variant.

L'invention concerne un FSH ou un variant FSH renfermant une sous-unité alpha et béta contenue dans des formulations, ainsi que des produits manufacturés. L'invention fournit des protéines et des acides nucléiques nouveaux et avantageux, des solutions pharmaceutiques polyvalentes, des formulations et des produits desdites protéines et desdits acides nucléiques dans lesquels aucun produit homologué pour l'usage commercial n'a existé antérieurement avec de telles indications d'emploi étendues. Ces produits sont particulièrement utilisés dans des régimes thérapeutiques, en vue d'accroître les teneurs en sérum de FSH ou d'un variant FSH pendant toute une période de traitement. L'invention répond ainsi inter alia à un besoin en produits appropriés de FSH ou d'un variant FSH.

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