Fsh glycosylation mutant

Details Fsh glycosylation mutant Fsh glycosylation mutant

C - Chemistry, Metallurgy

07

K

C07K 14/59 (2006.01) A61P 15/08 (2006.01) A61K 38/24 (2006.01) A61K 48/00 (2006.01) C12N 15/16 (2006.01)

Patent

CA 2535522

A novel FSH mutant with increased glycosylation and longer half-lifes for use in inducing folliculogenesis in human patients is described. The FSH mutant permits the use of lower cumulative doses of FSH to achieve the same or better clinical result.

L'invention concerne un nouveau mutant de la FSH à glycosylation améliorée et à demi-vies plus longues destiné à être utilisé dans l'induction de folliculogénèse chez des patients humains. Le mutant de la FSH permet l'utilisation de doses cumulatives plus faibles de la FSH, ce qui permet d'obtenir des résultats cliniques similaires ou améliorés.

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