Fucosyl transferases involved in adhesion molecule expression

Details Fucosyl transferases involved in adhesion molecule expression Fucosyl transferases involved in adhesion molecule expression

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 47/48 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 9/10 (2006.01) C12N 15/11 (2006.01) C12P 19/18 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2063244

2063244 9116900 PCTABS00008 We disclose DNA sequences designated clone 7.2 and clone 1, which cause cells transformed with them to express 1,3-fucosyl transferases and which are involved in CDX expression. We also disclose protein 7.2 and protein 1 which are encoded by clone 7.2 and clone 1, respectively. We also disclose Pseudo-X and Pseudo-X2, proteins which cause COS cells and CHO cells to bind to ELAM1 and to be recognized by .alpha.-CDX antibodies. We also disclose methods of using these molecules.

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