Fucosylated glycosides as inhibitors of bacterial adherence

Details Fucosylated glycosides as inhibitors of bacterial adherence Fucosylated glycosides as inhibitors of bacterial adherence

C - Chemistry, Metallurgy

07

K

C07K 14/765 (2006.01) A61K 31/70 (2006.01) A61K 38/38 (2006.01) A61K 47/48 (2006.01) C08G 81/02 (2006.01)

Patent

CA 2164961

Mono-, di-, tri- or oligosaccharide glycoside derivatives having at least one terminal group which is derived from L-fucose. The compounds are useful for therapy or prophylaxis in conditions involving infection by Heliobacter pylori of human gastric mucosa. Another object of the present invention is to provide a process for their preparation and pharmaceutical compositions.

Dérivés glycosidiques de mono, di, tri ou oligosaccharides présentant au moins un groupe terminal dérivé du L-fucose. Ces composés sont efficaces dans la thérapie ou la prophylaxie chez l'homme d'états relatifs à l'infection de la muqueuse gastrique par l'Heliobacter pylori; ainsi que leur méthode de préparation et celle de compositions pharmaceutiques les contenant.

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