Fullerene compositions for ameliorating dermatological...

Details Fullerene compositions for ameliorating dermatological... Fullerene compositions for ameliorating dermatological...

A - Human Necessities

61

K

A61K 8/42 (2006.01) A61K 8/37 (2006.01) A61P 17/00 (2006.01) A61Q 17/04 (2006.01) A61Q 19/00 (2006.01) A61K 31/015 (2006.01) A61K 31/16 (2006.01) A61K 31/194 (2006.01) A61K 31/215 (2006.01)

Patent

CA 2521818

This patent discloses a method of ameliorating a dermatological condition in the skin of a mammal, comprising administering a composition comprising a substituted fullerene to at least a portion of the skin of the mammal afflicted with the dermatological condition or potentially afflicted with the dermatological condition wherein the substituted fullerene comprises a fullerene core (Cn) and at least one of: (i) from 1 to 3 (>CX1X2) groups bonded to the fullerence core; (ii) from 1 to 18-X3 groups bonded to the fullerence core; (iii) from 1 to 6 -X4- groups bonded to the fullerence core; or (iv) from 1 to 6 dendrons bonded to the fullerence core.

Cette invention se rapporte à un procédé permettant d'améliorer l'état dermatologique de la peau d'un sujet mammifère et consistant à cet effet à administrer une composition comprenant un fullerène substitué sur au moins une partie de la peau du sujet mammifère souffrant d'une pathologie dermatologique présente ou potentielle, le fullerène substitué comprenant un noyau de fullerène (Cn) et au moins l'un des éléments suivants : (i) 1 à 3 groupes (>CX?1¿X?2¿) liés au noyau de fullerène; (ii) 1 à 18 groupes -X?3¿ liés au noyau de fullerène; (iii) 1 à 6 groupes -X?4¿- liés au noyau de fullerène ; ou (iv) 1 à 6 dendrites liées au noyau de fullerène.

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