Fullerene compositions for magnetic resonance spectroscopy...

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61K 49/06 (2006.01) A61K 49/18 (2006.01)

Patent

CA 2113996

2113996 9303771 PCTABS00020 Methods and compositions are disclosed for enhancing magnetic resonance imaging and spectroscopy which utilize derivatives of the even-numbered carbon clusters, known as ''fullerenes''. Perfluorinated carbon clusters of the formula CnFm, wherein n is in the range from 30-100 and m Í n, may be used for fluorine-19 imaging. Incorporating paramagnetic metal species into the carbon cluster cage improves fluorine and proton imaging.

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