Fully human high yield production system for improved...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 39/395 (2006.01) C07K 14/59 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/13 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2662226

The application relates to a method for producing a protein molecule composition having a defined glycosylation pattern, comprising: a) introducing in a host cell which is an immortalized human blood cell at least one nucleic acid encoding at least a part of said protein; and b) culturing said host cell under conditions which permit the production of said protein molecule composition; and c) isolating said protein molecule composition.

L'invention concerne un procédé de production d'une composition moléculaire protéinique présentant un modèle de glycosylation défini, procédé comprenant les étapes suivantes : (a) introduction d'une cellule hôte qui est une cellule sanguine humaine immortalisée d'au moins un acide nucléique codant au moins une partie de ladite protéine; et (b) culture de ladite cellule hôte dans des conditions permettant la production de ladite composition moléculaire protéinique; et (c) isolation de ladite composition moléculaire protéinique.

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