Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6-...

Details Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6-... Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6-...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2723989

4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N- methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate, pharmaceutical compositions containing the difumarate, the use of the difumarate in the treatment of hyperproliferative disorders such as cancer and processes for the manufacture of the difumarate are described.

L'invention porte sur le difumarate de 4-(3-chloro-2-fluoroanilino)-7-méthoxy-6-{[1-(N-méthylcarbamoylméthyl)pipéridin-4-yl]oxy}quinazoline, sur des compositions pharmaceutiques contenant le difumarate, sur l'utilisation du difumarate dans le traitement de troubles hyperprolifératifs tels que le cancer et sur des procédés pour la fabrication du difumarate.

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