A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/225 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/22 (2006.01) A61K 31/28 (2006.01) A61P 1/00 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)
Patent
CA 2329543
The invention relates to the use of one or more fumaric acid monoalkylester salts of general formula (I), optionally mixed with dialkyl fumarate of formula (II), wherein A represents a divalent cation of the series of Ca, Mg, Zn or Fe or a monovalent cation from the series Li, Na or K and n represents 1 or 2 depending on the type of cation, and optionally usual pharmaceutical adjuvants and carriers for the production of a pharmaceutical preparation in the form of microtablets or micropellets for the treatment of psoriatic arthritis, neurodermitis, psoriasis and Crohn's Enteritis regionalis.
L'invention concerne l'utilisation d'un ou plusieurs sels de monoalkylester d'acide fumarique, de formule générale (I), éventuellement mélangé(s) à du fumarate de dialkyle de formule (II), A représentant un cation bivalent de la série comprenant Ca, Mg, Zn ou Fe, ou un cation monovalent de la série Li, Na ou K, et n valant 1 ou 2 selon le type du cation, et éventuellement d'auxiliaires et d'excipients pharmaceutiques usuels pour produire une préparation pharmaceutique sous la forme de microcomprimés ou de micropastilles utilisés pour traiter l'arthrite psoriasique, la névrodermite, le psoriasis et la maladie de Crohn.
Joshi Rajendra Kumar
Strebel Hans-Peter
Biogen Idec International Gmbh
Fumapharm Ag
Macrae & Co.
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