Functional antibodies

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/395 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2638794

The invention is directed to novel antibodies, which comprise single domain binding sites. The antibodies can be bivalent or multivalent, and can be bispecific. The invention is further directed to monospecific and bispecific antibodies that bind to mPDGFR.alpha.. The antibodies can be administered alone or in combination with anti- angiogenic or anti-neoplastic drugs.

L'invention concerne de nouveaux anticorps qui comprennent des sites de liaison à domaine unique. Les anticorps peuvent être bivalents ou multivalents et ils peuvent être bispécifiques. L'invention concerne en outre des anticorps monospécifiques et bispécifiques qui se lient au mPDGFR.alpha.. Ces anticorps peuvent être administrés seuls ou en combinaison avec des médicaments anti-angiogènes ou anti-néoplasiques.

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