Functional assays for cholesterol absorption inhibitors

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) C12N 15/113 (2010.01) C07H 21/04 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12Q 1/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2592350

The present invention relates to functional assays performed in C.elegans worms that are useful for the identification of NPC1 L1 inhibitors. Compositions useful for the performance of such assays are also provided.

La présente invention concerne des essais fonctionnels effectués dans des vers C. elegans, lesquels essais sont utiles pour identifier des inhibiteurs de NPC1L1. L'invention concerne également des compositions utiles pour effectuer ces essais.

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