Functional dna clone for hepatitis c virus (hcv) and uses...

Details Functional dna clone for hepatitis c virus (hcv) and uses... Functional dna clone for hepatitis c virus (hcv) and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/867 (2006.01) A61K 39/29 (2006.01) A61P 31/14 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12N 1/15 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 5/14 (2006.01) C12N 5/16 (2006.01) C12N 7/00 (2006.01) C12N 15/51 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2283464

The present invention relates to the determination of an authentic HCV genome RNA sequences, to construction of infectious HCV DNA clones, and to use of the clones, or their derivatives, in therapeutic, vaccine, and diagnostic applications. The invention is also directed to HCV vectors, e.g., for gene therapy of gene vaccines.

La présente invention concerne l'analyse de séquences d'ARN génomique d'un authentique HCV, la construction de clones d'ADN du HCV infectieux, et l'utilisation de ces clones, ou de leurs dérivés, dans des applications thérapeutique, vaccinale et diagnostique. Cette invention concerne également des vecteurs HCV, utilisés par exemple en thérapie génique ou pour les vaccins géniques.

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