Functional expression of mammalian adenylyl cyclase in yeast

C - Chemistry – Metallurgy – 12 – N

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C12N 15/60 (2006.01) C12N 1/19 (2006.01) C12N 9/88 (2006.01) C12Q 1/527 (2006.01)

Patent

CA 2188950

Mammalian adenylyl cyclases are functionally expressed in yeast cells. The yeast cells may be used to screen for inhibitors or activators of the adenylyl cyclase, or of a regulator of adenylyl cyclase which is functionally co-expressed in the yeast cell.

Des adénylyle-cyclases de mammifère sont exprimées de manière fonctionnelle dans des cellules de levure. Ces cellules de levure peuvent être utilisées pour détecter des inhibiteurs ou des activateurs de l'adénylyle-cyclase ou d'un régulateur d'adénylyle-cyclase qui est co-exprimé de manière fonctionnelle dans la cellule de levure.

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