C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/25 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2467717
The invention provides methods and reagents for detecting a polymorphism associated with in an upstream region of the interleukin-1 beta (IL-B) gene (IL-1B(-3737)) that affects transcription of the gene and susceptibility to inflammatory and infectious diseases such as periodontal disease and ALzheimer's disease.
La présente invention concerne des procédés et des réactifs visant à détecter un polymorphisme associé à une région amont du gène IL-1B(-3737), qui est celui de l'interleukine-1 bêta (IL-B). Ce polymorphisme affecte, d'une part la transcription du gène, et d'autre part la susceptibilité à des affections inflammatoires et infectieuses, et notamment la parodontopathie et la maladie d'Alzheimer.
Aziz Nazneen
Duff Gordon W.
Hsieh Chung Ming
Kornman Kenneth S.
Wyllie David
Borden Ladner Gervais Llp
Interleukin Genetics Inc.
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