Functionalization of carotenoid compounds

Details Functionalization of carotenoid compounds Functionalization of carotenoid compounds

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C07K 14/195 (2006.01) C12N 5/10 (2006.01) C12N 9/04 (2006.01) C12N 15/10 (2006.01) C12N 15/31 (2006.01) C12N 15/52 (2006.01) C12P 7/24 (2006.01) C12P 7/26 (2006.01) C12P 7/44 (2006.01)

Patent

CA 2474364

Genes isolated from Methylomonas sp. 16a have been determined to play a role in the carotenoid biosynthetic pathway. Specifically, crtN2 gene has the ability to produce omega-aldehyde functional groups on carotenogenic substrates, while the ald gene produced omega carboxyl functional groups. These genes will be useful for production of high levels of functionalized carotenoid compounds, especially those produced in microorganisms which metabolize single carbon substrates.

On a déterminé que les gènes isolés à partir de <i>Methylomonas sp.</i> 16<i>a</i> ont un rôle dans la voie de synthèse des caroténoïdes biosynthetiques. Le gène <i> crt</i>N2 a notamment la capacité de produire des groupes fonctionnels d'oméga-aldéhyde sur substrats caroténogéniques, avec le gène <i> ald</i> qui produit des groups fonctionnels carboxyles oméga. Ces gènes peuvent être utiles pour produire des composés caroténoïdes fonctionnalisés en quantités importantes, notamment ceux produits dans les micro-organismes qui métabolisent des substrats de carbone uniques.

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