Functionalized compositions for improved immobilization

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07K 1/00 (2006.01) C07K 1/04 (2006.01) C07K 17/00 (2006.01) C12N 11/00 (2006.01) G01N 21/64 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2464144

The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to linker groups of 2-1000 atoms length. The present invention also contemplates the use of bifunctional bridge molecules to link two or more entities, wherein the functional groups of the bridge molecules are the novel reactive groups of the present invention.

La présente invention concerne le couplage covalent amélioré de plusieurs entités telles que des biomolécules, des compositions polymères, des molécules ou matières organiques et inorganiques, et analogues, y-compris leurs combinaisons, au moyen d'au moins un nouveau groupe réactif attaché à des groupes de liaison de 2-1000 atomes de long. L'invention concerne également l'utilisation de molécules de pontage bifonctionnelles pour relier plusieurs entités, les groupes fonctionnels des molécules de pontage étant les nouveaux groupes réactifs de la présente invention.

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